HPCCC instruments allow you to add an orthogonal and complementary liquid chromatographic technique to your laboratory without major changes to your current workflows. In contrast to solid phase techniques, such as reverse or normal phase liquid chromatography or SFC, the HPCCC stationary phase is a liquid rather than a solid. High resolution separations are possible due only to differences in the liquid-liquid partitioning behavior of sample solutes. Separations are dependent on improving selectivity, a powerful alternative to increasing efficiency when tackling difficult chromatographic separation problems.